Context: Split thickness skin grafting (STSG) restores cutaneous cover over wounds thus protecting the underlying surface from contamination, fluid loss and stimulates healing.Autologous platelet rich plasma (PRP) provides a large number of platelets and high concentration of growth factors which promote overall uptake of STSG.Aims: The aim of this study was to assess the immediate, subsequent adhesion and final take of STSG with application of PRP over recipient site.Methods and Material: 1 year Randomised Control Trial where 80 wounds of various aetiologies were randomised into intervention group (n=40) which received PRP before placing STSG on Sundowner Winds at Montecito during the Sundowner Winds Experiment recipient site and control group (n=40) in which the graft was fixed in place with sutures alone.Immediate graft adhesion and subsequent graft uptake were compared between the two groups and statistical analysis was done with: SPSS Version 20.
Results: Irrespective of aetiology, and size, among a total of 80 wounds 87.5% grafts had adhered by 1st minute of application in the intervention group compared to nil in control group (p0.05) Conclusions: Application of topical PRP facilitates STSG uptake.It decreases operative time by decreasing mobility of graft over the wound bed.Thus, use of PRP improves Persistent Infection of Pets within a Household with Three Bartonella Species outcome of split thickness skin graft in wounds of various aetiologies and we recommend use of the same at recipient site of STSG.
CTRI/2021/06/034401.